Each active in our products is well studied and chosen for their strong performance and potency. Below is what those studies actually measured, who ran them, and what the numbers mean.
Our cosmetic efficacy data is generated by the companies that develop the raw actives, study them and promote them on the marketplace. They test a single ingredient at a defined concentration, under controlled conditions, and publish the protocol. This is real evidence that we cite directly, however it is not the same as a clinical trial of a finished product, and we don’t present it as one.
Uttwiler Spätlauber is an endangered Swiss apple, once prized for staying edible through a long winter without shrivelling. Mibelle Biochemistry cultures its stem cells rather than harvesting the fruit, then encapsulates them in liposomes. The interest is in longevity: skin’s own stem cells decline in number and activity with age, and depletion is widely regarded as a primary driver of skin ageing.
A signalling peptide that works through the TGF-β pathway, prompting fibroblasts to produce more of the collagen that gives skin its structure. It also suppresses MMP-9, one of the enzymes that breaks collagen down, so it acts on both sides of the same equation.
Elastin is what lets skin snap back. Building it requires two proteins, FBLN5 and LOXL1, that assemble loose tropoelastin into mature, functional fibres; both decline with age. This peptide raises the levels of both, which is a different mechanism from simply making more collagen.
Myrothamnus flabellifolia survives total dehydration for years, then re-greens within hours of rain. Glycoin is the molecule that makes that possible, protecting the plant’s cell membranes while dry and restarting its metabolism when water returns. In skin the interest is energy: ATP production in skin cells declines with age, and most repair depends on it.
Not everything has to work over weeks. This cassava-derived glucan forms a thin viscoelastic film on the skin surface that tightens as it sets, which is why the effect is visible within half an hour rather than a month. It sits alongside the slower actives rather than replacing them.
Not every ingredient carries a headline number, and several are chosen for how they behave alongside the actives above rather than for an effect of their own.
Data on this page is drawn from technical documentation published by the companies that manufacture each active: Mibelle Biochemistry, Lipotec, Silab, bitop AG, Barnet Products, Botanigenics and DSM. Protocols, sample sizes and concentrations are reproduced as stated in that documentation. Where a figure is in-vitro, it is labelled as such. We have not conducted clinical testing on finished ÆONS products, and nothing here should be read as a medical claim.
questions about a formulastart with step one.